| 3. Round | 22/07/2000 | Grasshopper Club Zürich | - | Neuchâtel Xamax FC | 6:0 | ||||
| 6. Round | 12/08/2000 | Neuchâtel Xamax FC | - | FC St. Gallen | 2:1 | ||||
| 7. Round | 19/08/2000 | FC Lugano | - | Neuchâtel Xamax FC | 3:0 |  |
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| 8. Round | 26/08/2000 | Neuchâtel Xamax FC | - | FC Aarau | 1:5 | ||||
| 9. Round | 05/09/2000 | FC Zürich | - | Neuchâtel Xamax FC | 3:0 | ||||
| 11. Round | 17/09/2000 | FC Sion | - | Neuchâtel Xamax FC | 2:1 | ||||
| 12. Round | 22/09/2000 | Neuchâtel Xamax FC | - | FC Luzern | 1:1 | ||||
| 13. Round | 01/10/2000 | FC Basel 1893 | - | Neuchâtel Xamax FC | 5:1 | ||||
| 14. Round | 14/10/2000 | Neuchâtel Xamax FC | - | Grasshopper Club Zürich | 1:3 | ||||
| 15. Round | 21/10/2000 | Yverdon Sport FC | - | Neuchâtel Xamax FC | 4:0 | ||||
| 16. Round | 29/10/2000 | Neuchâtel Xamax FC | - | Servette FC | 2:1 | ||||
| 18. Round | 05/11/2000 | Neuchâtel Xamax FC | - | FC Lugano | 1:0 | ||||
| 20. Round | 26/11/2000 | Neuchâtel Xamax FC | - | FC Zürich | 3:1 |
Switzerland