| 1. Round | 18/09/2021 | Correcaminos UAT II | - | Tecos Fútbol Club | 2:1 | ||||
| 2. Round | 25/09/2021 | Tecos Fútbol Club | - | Colima FC | 1:1 |  |
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| 3. Round | 02/10/2021 | Leones Negros II | - | Tecos Fútbol Club | 0:0 | ||||
| 4. Round | 09/10/2021 | Tecos Fútbol Club | - | Coras de Nayarit | 2:1 | ||||
| 7. Round | 23/10/2021 | Alacranes de Durango | - | Tecos Fútbol Club | 2:0 |
Mexico