| 11. Round | 06/10/2018 | Slovan Bratislava | - | FK Senica | 2:2 | ||||
| 12. Round | 20/10/2018 | Spartak Trnava | - | FK Senica | 4:1 | ||||
| 13. Round | 27/10/2018 | FK Senica | - | ŠKF Sereď | 0:0 | ||||
| 14. Round | 03/11/2018 | FK Senica | - | Zlaté Moravce | 3:0 | ||||
| 15. Round | 10/11/2018 | FK Železiarne Podbrezová | - | FK Senica | 2:4 | ||||
| 16. Round | 24/11/2018 | FK Senica | - | MFK Zemplín Michalovce | 2:4 | ||||
| 17. Round | 01/12/2018 | FC Nitra | - | FK Senica | 1:0 | ||||
| 18. Round | 08/12/2018 | FK Senica | - | MFK Ružomberok | 1:1 |  |
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| 19. Round | 16/02/2019 | AS Trenčín | - | FK Senica | 3:0 | ||||
| 20. Round | 23/02/2019 | FK Senica | - | MŠK Žilina | 0:1 | ||||
| 21. Round | 02/03/2019 | FC DAC 1904 | - | FK Senica | 1:0 | ||||
| 22. Round | 09/03/2019 | FK Senica | - | Slovan Bratislava | 1:2 |
Cape Verde