| 1. Round | 25/06/2022 | Mazatlán FC [U16] | - | Club Tijuana [U16] | 0:0 | ||||
| 2. Round | 02/07/2022 | Club Tijuana [U16] | - | Santos Laguna [U16] | 1:2 | ||||
| 3. Round | 09/07/2022 | Atlas Guadalajara [U16] | - | Club Tijuana [U16] | 1:0 | ||||
| 4. Round | 16/07/2022 | Club Tijuana [U16] | - | UANL Tigres [U16] | 2:0 | ||||
| 5. Round | 23/07/2022 | Club León [U16] | - | Club Tijuana [U16] | 1:2 | ||||
| 6. Round | 30/07/2022 | Club Tijuana [U16] | - | Deportivo Guadalajara [U16] | 2:2 | ||||
| 8. Round | 13/08/2022 | CF Monterrey [U16] | - | Club Tijuana [U16] | 3:0 | ||||
| 10. Round | 27/08/2022 | Club Tijuana [U16] | - | Mazatlán FC [U16] | 0:1 | ||||
| 12. Round | 10/09/2022 | Club Tijuana [U16] | - | CF Monterrey [U16] | 0:4 | ||||
| 14. Round | 25/09/2022 | Deportivo Guadalajara [U16] | - | Club Tijuana [U16] | 4:1 |  |
|||
| 16. Round | 08/10/2022 | UANL Tigres [U16] | - | Club Tijuana [U16] | 4:1 | ||||
| 15. Round | 12/10/2022 | Club Tijuana [U16] | - | Club León [U16] | 4:1 | ||||
| 17. Round | 15/10/2022 | Club Tijuana [U16] | - | Atlas Guadalajara [U16] | 0:2 | ||||
| 18. Round | 22/10/2022 | Santos Laguna [U16] | - | Club Tijuana [U16] | 0:1 |
USA