| 1. Round | 18/07/2021 | FK Znamya Noginsk | - | FK Strogino Moskva | 3:1 |  |
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| 2. Round | 24/07/2021 | SKA-Khabarovsk 2 | - | FK Znamya Noginsk | 3:0 | ||||
| 4. Round | 07/08/2021 | FK Znamya Noginsk | - | FK Saransk | 0:5 | ||||
| 6. Round | 21/08/2021 | FK Znamya Noginsk | - | FK Kolomna | 5:3 | ||||
| 7. Round | 29/08/2021 | Rodina Moskva | - | FK Znamya Noginsk | 3:0 | ||||
| 8. Round | 03/09/2021 | FK Znamya Noginsk | - | FK Peresvet Podolsk | 0:2 | ||||
| 10. Round | 14/09/2021 | FK Znamya Noginsk | - | FK Saturn | 0:1 | ||||
| 14. Round | 04/10/2021 | FK Saransk | - | FK Znamya Noginsk | 1:0 | ||||
| 15. Round | 10/10/2021 | FK Znamya Noginsk | - | Kvant Obninsk | 1:1 | ||||
| 19. Round | 31/10/2021 | FK Znamya Noginsk | - | Metallurg Vidnoye | 3:1 | ||||
| 20. Round | 04/11/2021 | FK Saturn | - | FK Znamya Noginsk | 5:0 | ||||
| 21. Round | 10/11/2021 | FK Znamya Noginsk | - | FK Khimki 2 | 0:5 | ||||
| 22. Round | 14/11/2021 | FK Strogino Moskva | - | FK Znamya Noginsk | 4:3 | ||||
| 5. Round | 17/11/2021 | Kvant Obninsk | - | FK Znamya Noginsk | 1:1 |
Russia