| FB | 01/08/21 | Santos Laguna [U18] | - | Cruz Azul [U18] | 1:2 | ||||
| FB | 02/10/21 | Santos Laguna [U18] | - | Mazatlán FC [U18] | 3:0 | ||||
| FB | 24/10/21 | Santos Laguna [U18] | - | Deportivo Toluca [U18] | 3:1 | ||||
| 06/11/21 | UANL Tigres [U16] | - | Santos Laguna [U16] | 4:0 | |||||
| FB | 18/11/21 | Santos Laguna [U18] | - | Club Necaxa [U18] | 1:0 |
Mexico