| 1. Round | 03/06/2022 | Arsenal de Sarandí II | - | Boca Juniors II | 2:0 | ||||
| 2. Round | 09/06/2022 | Boca Juniors II | - | Central Córdoba SdE II | 3:1 | ||||
| 3. Round | 13/06/2022 | Tigre II | - | Boca Juniors II | 0:2 |  |
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| 4. Round | 17/06/2022 | Boca Juniors II | - | Barracas Central II | 0:1 | ||||
| 7. Round | 08/07/2022 | Boca Juniors II | - | San Lorenzo II | 2:1 |  |
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| 8. Round | 13/07/2022 | Talleres de Córdoba II | - | Boca Juniors II | 1:2 | ||||
| 9. Round | 18/07/2022 | Boca Juniors II | - | Argentinos Juniors II | 3:1 | |
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| 10. Round | 24/07/2022 | Estudiantes II | - | Boca Juniors II | 0:3 | |
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| 11. Round | 29/07/2022 | Boca Juniors II | - | Patronato de Paraná II | 1:0 | ||||
| 12. Round | 05/08/2022 | Platense II | - | Boca Juniors II | 0:0 | ||||
| 13. Round | 11/08/2022 | Boca Juniors II | - | Racing Club II | 3:0 | ||||
| 15. Round | 22/08/2022 | Boca Juniors II | - | Defensa y Justicia II | 3:0 |
Argentina