| 3. Round | 13/08/2011 | Unión San Felipe | - | Deportes Iquique | 2:1 |  |
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| 4. Round | 21/08/2011 | Deportes Iquique | - | Santiago Morning | 4:2 | ||||
| 5. Round | 24/08/2011 | Universidad de Concepción | - | Deportes Iquique | 3:1 | ||||
| 6. Round | 28/08/2011 | Ñublense | - | Deportes Iquique | 1:2 | ||||
| 8. Round | 17/09/2011 | Santiago Wanderers | - | Deportes Iquique | 2:2 | ||||
| 9. Round | 24/09/2011 | Deportes Iquique | - | Unión Española | 1:5 | ||||
| 10. Round | 29/09/2011 | Deportes Iquique | - | La Serena | 1:1 | ||||
| 11. Round | 02/10/2011 | Universidad de Chile | - | Deportes Iquique | 2:2 | ||||
| 13. Round | 22/10/2011 | Audax Italiano | - | Deportes Iquique | 3:0 | ||||
| 15. Round | 05/11/2011 | Unión La Calera | - | Deportes Iquique | 1:2 | ||||
| 16. Round | 19/11/2011 | Deportes Iquique | - | Colo-Colo | 1:1 |
Argentina