| 1. Round | 22/07/2017 | Lobos BUAP | - | Santos Laguna | 2:2 | ||||
| 2. Round | 29/07/2017 | Gallos Blancos | - | Lobos BUAP | 0:4 | ||||
| 14. Round | 21/10/2017 | Lobos BUAP | - | Cruz Azul | 3:0 | ||||
| 15. Round | 29/10/2017 | Club Necaxa | - | Lobos BUAP | 5:0 | ||||
| 16. Round | 04/11/2017 | Lobos BUAP | - | CF Monterrey | 2:1 | ||||
| 17. Round | 18/11/2017 | Puebla FC | - | Lobos BUAP | 0:1 |
Uruguay