| 1. Round | 15/07/2000 | FC Luzern | - | Neuchâtel Xamax FC | 2:0 | ||||
| 2. Round | 18/07/2000 | Neuchâtel Xamax FC | - | FC Basel 1893 | 2:0 |  |
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| 3. Round | 22/07/2000 | Grasshopper Club Zürich | - | Neuchâtel Xamax FC | 6:0 | ||||
| 4. Round | 29/07/2000 | Neuchâtel Xamax FC | - | Yverdon Sport FC | 1:1 | ||||
| 5. Round | 04/08/2000 | Servette FC | - | Neuchâtel Xamax FC | 5:2 | ||||
| 6. Round | 12/08/2000 | Neuchâtel Xamax FC | - | FC St. Gallen | 2:1 | ||||
| 7. Round | 19/08/2000 | FC Lugano | - | Neuchâtel Xamax FC | 3:0 | ||||
| 8. Round | 26/08/2000 | Neuchâtel Xamax FC | - | FC Aarau | 1:5 |  |
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| 9. Round | 05/09/2000 | FC Zürich | - | Neuchâtel Xamax FC | 3:0 | |
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| 10. Round | 09/09/2000 | Neuchâtel Xamax FC | - | Lausanne Sports | 2:4 | |
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| 11. Round | 17/09/2000 | FC Sion | - | Neuchâtel Xamax FC | 2:1 | ||||
| 12. Round | 22/09/2000 | Neuchâtel Xamax FC | - | FC Luzern | 1:1 | ||||
| 13. Round | 01/10/2000 | FC Basel 1893 | - | Neuchâtel Xamax FC | 5:1 | ||||
| 16. Round | 29/10/2000 | Neuchâtel Xamax FC | - | Servette FC | 2:1 | |
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| 19. Round | 19/11/2000 | FC Aarau | - | Neuchâtel Xamax FC | 2:0 |
Portugal
Switzerland