| 1. Round | 09/01/2021 | Atlas Guadalajara | - | CF Monterrey | 0:2 | ||||
| 2. Round | 18/01/2021 | Gallos Blancos | - | Atlas Guadalajara | 1:0 | ||||
| 6. Round | 16/02/2021 | CF Pachuca | - | Atlas Guadalajara | 0:1 | ||||
| 7. Round | 21/02/2021 | Atlas Guadalajara | - | CF América | 3:0 dec. | ||||
| 8. Round | 27/02/2021 | Deportivo Toluca | - | Atlas Guadalajara | 0:0 | ||||
| 10. Round | 06/03/2021 | Atlas Guadalajara | - | FC Juárez | 2:0 | ||||
| 12. Round | 21/03/2021 | Cruz Azul | - | Atlas Guadalajara | 3:2 |
Mexico