2. Round | 02/08/2021 | Atlético San Luis [U20] | - | Gallos Blancos [U20] | 0:2 | ||||
3. Round | 08/08/2021 | Pumas UNAM [U20] | - | Atlético San Luis [U20] | 5:3 | ||||
4. Round | 12/08/2021 | Atlético San Luis [U20] | - | Club Necaxa [U20] | 1:2 | ||||
8. Round | 10/09/2021 | Puebla FC [U20] | - | Atlético San Luis [U20] | 2:2 | ||||
16. Round | 31/10/2021 | Atlético San Luis [U20] | - | CF Monterrey [U20] | 3:1 |