| 14. Round | 28/10/2017 | Slovan Bratislava | - | FK Senica | 2:2 | ||||
| 15. Round | 05/11/2017 | FK Senica | - | MŠK Žilina | 4:1 | ||||
| 16. Round | 18/11/2017 | FC Nitra | - | FK Senica | 0:0 | ||||
| 17. Round | 25/11/2017 | FK Senica | - | 1. FC Tatran Prešov | 1:0 | ||||
| 18. Round | 02/12/2017 | Zlaté Moravce | - | FK Senica | 3:0 | ||||
| 19. Round | 09/12/2017 | FK Senica | - | MFK Zemplín Michalovce | 1:1 | ||||
| 20. Round | 18/02/2018 | FK Senica | - | FC DAC 1904 | 0:2 | ||||
| 21. Round | 24/02/2018 | Spartak Trnava | - | FK Senica | 1:0 |
Slovakia