| 6. Round | 17/10/2020 | Shakhtar Donetsk | - | FK Lviv | 5:1 | ||||
| 8. Round | 30/10/2020 | Shakhtar Donetsk | - | FK Mariupol | 4:1 | ||||
| 9. Round | 08/11/2020 | Dinamo Kiev | - | Shakhtar Donetsk | 0:3 | ||||
| 10. Round | 21/11/2020 | Shakhtar Donetsk | - | FK Oleksandriya | 1:1 |  |
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| 11. Round | 28/11/2020 | SK Dnipro-1 | - | Shakhtar Donetsk | 0:1 | ||||
| 20. Round | 04/04/2021 | Vorskla Poltava | - | Shakhtar Donetsk | 0:2 | ||||
| 21. Round | 10/04/2021 | FK Mariupol | - | Shakhtar Donetsk | 0:3 | ||||
| 23. Round | 25/04/2021 | FK Oleksandriya | - | Shakhtar Donetsk | 2:0 |
Brazil