| 1. Round | 05/08/2005 | Slavia Praha | - | Vysočina Jihlava | 1:1 | ||||
| 2. Round | 14/08/2005 | FK Teplice | - | Slavia Praha | 1:0 | ||||
| 3. Round | 20/08/2005 | Slavia Praha | - | FK Jablonec 97 | 3:2 | ||||
| 4. Round | 27/08/2005 | Sigma Olomouc | - | Slavia Praha | 4:3 | ||||
| 5. Round | 10/09/2005 | Viktoria Plzeň | - | Slavia Praha | 1:1 | ||||
| 6. Round | 18/09/2005 | Slavia Praha | - | Tescoma Zlín | 1:0 | ||||
| 7. Round | 24/09/2005 | FK Marila Příbram | - | Slavia Praha | 2:2 |  |
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| 8. Round | 03/10/2005 | Slavia Praha | - | FK Mladá Boleslav | 2:1 | ||||
| 9. Round | 15/10/2005 | FK SIAD Most | - | Slavia Praha | 0:3 |  |
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| 10. Round | 23/10/2005 | Slavia Praha | - | AC Sparta Praha | 4:1 | |
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| 11. Round | 31/10/2005 | 1. FC Brno | - | Slavia Praha | 1:0 | ||||
| 12. Round | 06/11/2005 | Slavia Praha | - | 1. FC Slovácko | 2:0 | ||||
| 13. Round | 19/11/2005 | Slovan Liberec | - | Slavia Praha | 3:3 | |
Czech Republic