| 1. Round | 06/08/2022 | FC Biel/Bienne | - | FC Stade Nyonnais | 0:3 | ||||
| 2. Round | 13/08/2022 | FC Chiasso | - | FC Biel/Bienne | annull. | ||||
| 3. Round | 20/08/2022 | FC Biel/Bienne | - | FC Luzern II | 1:6 | ||||
| 4. Round | 27/08/2022 | FC Rapperswil-Jona | - | FC Biel/Bienne | 1:0 |  |
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| 5. Round | 03/09/2022 | FC Biel/Bienne | - | FC Zürich II | 4:2 |  |
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| 6. Round | 10/09/2022 | SC Brühl | - | FC Biel/Bienne | 1:0 | ||||
| 7. Round | 18/09/2022 | FC Biel/Bienne | - | FC Bavois | 0:1 | |
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| 8. Round | 24/09/2022 | Etoile Carouge FC | - | FC Biel/Bienne | 3:2 | ||||
| 9. Round | 02/10/2022 | FC Biel/Bienne | - | FC Breitenrain Bern | 1:1 | ||||
| 10. Round | 08/10/2022 | FC Bulle | - | FC Biel/Bienne | 3:0 | ||||
| 11. Round | 15/10/2022 | FC Biel/Bienne | - | SC YF/Juventus Zürich | 2:1 | ||||
| 12. Round | 19/10/2022 | FC Biel/Bienne | - | FC Baden | 1:1 | ||||
| 13. Round | 22/10/2022 | SC Kriens | - | FC Biel/Bienne | 4:2 | ||||
| 14. Round | 30/10/2022 | FC Biel/Bienne | - | FC St. Gallen II | 0:1 |  |
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| 17. Round | 19/11/2022 | FC Basel 1893 II | - | FC Biel/Bienne | 0:0 | ||||
| 18. Round | 25/11/2022 | FC Stade Nyonnais | - | FC Biel/Bienne | 3:0 |
Switzerland