| 1. Round | 04/02/2012 | Libertad | - | Club Nacional | 1:0 | ||||
| 2. Round | 12/02/2012 | Libertad | - | Sportivo Luqueño | 1:0 | ||||
| 3. Round | 20/02/2012 | Tacuary | - | Libertad | 1:1 | ||||
| 4. Round | 25/02/2012 | Libertad | - | Guaraní | 2:2 | ||||
| 6. Round | 09/03/2012 | Libertad | - | Club Olimpia | 0:1 | ||||
| 7. Round | 17/03/2012 | Cerro Porteño | - | Libertad | 1:0 | ||||
| 8. Round | 25/03/2012 | Libertad | - | Sportivo Carapeguá | 1:1 |  |
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| 10. Round | 08/04/2012 | Libertad | - | Independiente CG | 1:1 | ||||
| 14. Round | 27/04/2012 | Libertad | - | Tacuary | 2:1 | ||||
| 15. Round | 05/05/2012 | Guaraní | - | Libertad | 2:3 | |
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| 16. Round | 12/05/2012 | Libertad | - | Sol de América | 0:1 | ||||
| 18. Round | 17/06/2012 | Libertad | - | Cerro Porteño | 2:1 | ||||
| 19. Round | 26/06/2012 | Sportivo Carapeguá | - | Libertad | 2:2 |  |
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| 20. Round | 01/07/2012 | Libertad | - | Cerro de Franco | 2:0 | |
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Paraguay