| Group H | 16/09/2021 | Qarabağ FK | - | FC Basel 1893 | 0:0 | ||||
| Group H | 30/09/2021 | FC Basel 1893 | - | FK Kairat | 4:2 |  |
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| Group H | 21/10/2021 | FC Basel 1893 | - | Omonia Nikosia | 3:1 | ||||
| Group H | 04/11/2021 | Omonia Nikosia | - | FC Basel 1893 | 1:1 | ||||
| Group H | 25/11/2021 | FK Kairat | - | FC Basel 1893 | 2:3 | ||||
| Round of 16 | 17/03/2022 | FC Basel 1893 | - | Olympique Marseille | 1:2 |
Switzerland