1. Round | 24/07/2021 | FK Pardubice | - | MFK Karviná | 2:2 | ||||
2. Round | 31/07/2021 | Sigma Olomouc | - | FK Pardubice | 3:2 | ||||
3. Round | 08/08/2021 | FK Pardubice | - | FK Mladá Boleslav | 1:1 | ||||
4. Round | 15/08/2021 | Baník Ostrava | - | FK Pardubice | 3:1 | ||||
5. Round | 21/08/2021 | FK Pardubice | - | Bohemians Praha 1905 | 3:0 | ||||
6. Round | 28/08/2021 | 1. FC Slovácko | - | FK Pardubice | 2:1 | ||||
7. Round | 11/09/2021 | FK Pardubice | - | Slovan Liberec | 2:2 | ||||
8. Round | 17/09/2021 | FC Hradec Králové | - | FK Pardubice | 2:0 | ||||
12. Round | 23/10/2021 | FK Pardubice | - | FC Fastav Zlín | 0:0 | ||||
13. Round | 31/10/2021 | FK Jablonec | - | FK Pardubice | 1:1 | ||||
15. Round | 21/11/2021 | FK Teplice | - | FK Pardubice | 1:2 | ||||
16. Round | 27/11/2021 | FK Pardubice | - | Sigma Olomouc | 1:5 |