| 1. Round | 09/08/2022 | MFK Karviná [Youth B] | - | Slavia Praha [Youth B] | 0:5 | ||||
| 2. Round | 13/08/2022 | FK Dukla Praha [Youth B] | - | MFK Karviná [Youth B] | 3:3 | ||||
| 4. Round | 26/08/2022 | MFK Karviná [Youth B] | - | FK Příbram [Youth B] | 5:0 | ||||
| 8. Round | 30/08/2022 | MFK Karviná [Youth B] | - | FK Pardubice [Youth B] | 2:0 |  |
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| 5. Round | 03/09/2022 | FC Zlín [Youth B] | - | MFK Karviná [Youth B] | 3:0 |  |
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| 9. Round | 01/10/2022 | Banik Ostrava [Youth B] | - | MFK Karviná [Youth B] | 5:1 | ||||
| 12. Round | 21/10/2022 | MFK Karviná [Youth B] | - | 1. FC Slovácko [Youth B] | 0:3 | ||||
| 14. Round | 05/11/2022 | MFK Karviná [Youth B] | - | Viktoria Plzeň [Youth B] | 0:3 |
Czech Republic