| 2. Round | 29/08/2021 | RKVV Westlandia | - | USV Hercules | 1:1 | ||||
| 4. Round | 12/09/2021 | JOS Watergraafsmeer | - | USV Hercules | 1:4 | ||||
| 6. Round | 26/09/2021 | ADO '20 | - | USV Hercules | 4:2 | ||||
| 8. Round | 10/10/2021 | VV Gemert | - | USV Hercules | 2:2 | ||||
| 10. Round | 31/10/2021 | RKVV DEM | - | USV Hercules | 1:0 | ||||
| 11. Round | 07/11/2021 | USV Hercules | - | OFC Oostzaan | 2:3 | ||||
| 12. Round | 14/11/2021 | VV Dongen | - | USV Hercules | 2:2 | ||||
| 13. Round | 21/11/2021 | USV Hercules | - | HVV Hollandia | 2:0 | ||||
| 14. Round | 28/11/2021 | VV Hoogland | - | USV Hercules | 1:2 |  |
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| 15. Round | 20/02/2022 | USV Hercules | - | Quick Den Haag | 1:3 | |
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| 7. Round | 09/03/2022 | USV Hercules | - | HSC'21 | 1:0 | |
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| 17. Round | 16/03/2022 | Blauw Geel '38 | - | USV Hercules | 0:1 | ||||
| 21. Round | 23/03/2022 | VV UNA | - | USV Hercules | 1:5 | ||||
| 20. Round | 27/03/2022 | USV Hercules | - | VV Dongen | 1:3 | ||||
| 27. Round | 24/04/2022 | USV Hercules | - | RKVV DEM | 0:1 | ||||
| 34. Round | 06/06/2022 | USV Hercules | - | ADO '20 | 3:3 |
Netherlands