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| 23/04/2022 | 18:30 | RKSV Groene Ster | - | EVV | 3:2 (2:0) | |
| 18:30 | VV UNA | - | Blauw Geel '38 | 0:1 (0:0) | ||
| 24/04/2022 | 13:00 | USV Hercules | - | RKVV DEM | 0:1 (0:0) | |
| 13:00 | ADO '20 | - | Unitas Gorinchem | 4:1 (2:0) | ||
| 13:00 | Quick Den Haag | - | HVV Hollandia | 4:0 (1:0) | ||
| 13:00 | RKVV Westlandia | - | VV Dongen | 3:2 (1:0) | ||
| 13:00 | JOS Watergraafsmeer | - | VV Hoogland | 1:3 (0:3) | ||
| 13:30 | HSC'21 | - | VV Gemert | 3:2 (2:1) | ||
| 13:30 | OSS '20 | - | OFC Oostzaan | 1:3 (1:0) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Gemert | 27 | 15 | 9 | 3 | 64:42 | 22 | 54 |
| 2 |
|
OFC Oostzaan | 27 | 15 | 4 | 8 | 56:45 | 11 | 49 |
| 3 |
|
RKSV Groene Ster | 27 | 13 | 7 | 7 | 41:35 | 6 | 46 |
| 4 |
|
ADO '20 | 27 | 13 | 5 | 9 | 48:36 | 12 | 44 |
| 5 |
|
VV Dongen | 27 | 11 | 10 | 6 | 46:35 | 11 | 43 |
| 6 |
|
USV Hercules | 27 | 13 | 3 | 11 | 50:36 | 14 | 42 |
| 7 |
|
OSS '20 | 27 | 13 | 4 | 10 | 50:39 | 11 | 42 |
| 8 |
|
VV UNA | 27 | 12 | 4 | 11 | 48:43 | 5 | 40 |
| 9 |
|
Blauw Geel '38 | 27 | 12 | 3 | 12 | 48:41 | 7 | 39 |
| 10 |
|
Quick Den Haag | 27 | 12 | 3 | 12 | 40:34 | 6 | 39 |
| 11 |
|
Unitas Gorinchem | 27 | 11 | 4 | 12 | 34:49 | -15 | 37 |
| 12 |
|
HSC'21 | 27 | 11 | 3 | 13 | 43:38 | 5 | 36 |
| 13 |
|
JOS Watergraafsmeer | 27 | 10 | 4 | 13 | 45:51 | -6 | 32 |
| 14 |
|
RKVV DEM | 27 | 9 | 5 | 13 | 26:40 | -14 | 32 |
| 15 |
|
EVV | 27 | 6 | 10 | 11 | 27:43 | -16 | 28 |
| 16 |
|
VV Hoogland | 27 | 8 | 4 | 15 | 29:52 | -23 | 28 |
| 17 |
|
HVV Hollandia | 27 | 8 | 3 | 16 | 29:44 | -15 | 27 |
| 18 |
|
RKVV Westlandia | 27 | 5 | 7 | 15 | 25:46 | -21 | 22 |
| Promotion | |
| Playoffs | |
| Relegation |
