| 1. Round | 05/06/2022 | Independiente II | - | San Lorenzo II | 0:1 | ||||
| 2. Round | 09/06/2022 | Talleres de Córdoba II | - | Independiente II | 0:4 |  |
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| 3. Round | 15/06/2022 | Independiente II | - | Argentinos Juniors II | 0:3 | ||||
| 4. Round | 19/06/2022 | Estudiantes II | - | Independiente II | 1:1 | |
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| 5. Round | 26/06/2022 | Independiente II | - | Patronato de Paraná II | 7:1 | |
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| 6. Round | 01/07/2022 | Platense II | - | Independiente II | 0:1 | |
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| 8. Round | 14/07/2022 | Rosario Central II | - | Independiente II | 5:1 | ||||
| 9. Round | 19/07/2022 | Independiente II | - | Defensa y Justicia II | 0:0 |
Argentina