| 1. Round | 06/08/2022 | Vysočina Jihlava [Youth B] | - | 1. FC Slovácko [Youth B] | 2:1 | ||||
| 2. Round | 13/08/2022 | 1. FC Slovácko [Youth B] | - | FK Pardubice [Youth B] | 3:1 | ||||
| 3. Round | 19/08/2022 | Banik Ostrava [Youth B] | - | 1. FC Slovácko [Youth B] | 4:3 | ||||
| 4. Round | 27/08/2022 | 1. FC Slovácko [Youth B] | - | Dynamo České Budějovice [Youth B] | 4:0 | ||||
| 9. Round | 01/10/2022 | 1. FC Slovácko [Youth B] | - | FC Zbrojovka Brno [Youth B] | 0:2 | ||||
| 10. Round | 08/10/2022 | Slavia Praha [Youth B] | - | 1. FC Slovácko [Youth B] | 2:2 | ||||
| 11. Round | 14/10/2022 | 1. FC Slovácko [Youth B] | - | FK Dukla Praha [Youth B] | 1:1 | ||||
| 12. Round | 21/10/2022 | MFK Karviná [Youth B] | - | 1. FC Slovácko [Youth B] | 0:3 | ||||
| 14. Round | 26/10/2022 | FC Zlín [Youth B] | - | 1. FC Slovácko [Youth B] | 1:1 | ||||
| 13. Round | 29/10/2022 | 1. FC Slovácko [Youth B] | - | FK Příbram [Youth B] | 9:2 | ||||
| 15. Round | 12/11/2022 | 1. FC Slovácko [Youth B] | - | FC Hradec Králové [Youth B] | 0:1 | ||||
| 26. Round | 12/05/2023 | FK Dukla Praha [Youth B] | - | 1. FC Slovácko [Youth B] | 1:1 |
Czech Republic