| 2. Round | 13/08/2022 | FK Dukla Praha [Youth] | - | MFK Karviná [Youth] | 2:2 | ||||
| 3. Round | 19/08/2022 | MFK Karviná [Youth] | - | AC Sparta Praha [Youth] | 2:3 | ||||
| 4. Round | 26/08/2022 | MFK Karviná [Youth] | - | FK Příbram [Youth] | 5:1 | ||||
| 8. Round | 30/08/2022 | MFK Karviná [Youth] | - | FK Pardubice [Youth] | 3:0 | ||||
| 5. Round | 03/09/2022 | FC Zlín [Youth] | - | MFK Karviná [Youth] | 5:0 | ||||
| 7. Round | 17/09/2022 | Vysočina Jihlava [Youth] | - | MFK Karviná [Youth] | 6:2 | ||||
| 11. Round | 14/10/2022 | Sigma Olomouc [Youth] | - | MFK Karviná [Youth] | 4:0 | ||||
| 14. Round | 05/11/2022 | MFK Karviná [Youth] | - | Viktoria Plzeň [Youth] | 3:3 |  |
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| 15. Round | 12/11/2022 | FC Zbrojovka Brno [Youth] | - | MFK Karviná [Youth] | 1:1 |
Poland