| Round of 16 | 28/04/2010 | Deportivo Guadalajara | - | Vélez Sarsfield | 3:0 | ||||
| Round of 16 | 05/05/2010 | Vélez Sarsfield | - | Deportivo Guadalajara | 2:0 | ||||
| Quarter-finals | 12/05/2010 | Deportivo Guadalajara | - | Libertad | 3:0 | ||||
| Quarter-finals | 19/05/2010 | Libertad | - | Deportivo Guadalajara | 2:0 |  |
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| Semi-finals | 28/07/2010 | Deportivo Guadalajara | - | Universidad de Chile | 1:1 | |
Mexico