| 20. Round | 05/02/2022 | FK Teplice | - | Bohemians Praha 1905 | 1:0 | ||||
| 21. Round | 12/02/2022 | Bohemians Praha 1905 | - | FC Fastav Zlín | 1:0 | ||||
| 23. Round | 26/02/2022 | Bohemians Praha 1905 | - | Baník Ostrava | 0:2 | ||||
| 24. Round | 05/03/2022 | Sigma Olomouc | - | Bohemians Praha 1905 | 0:0 | ||||
| 25. Round | 12/03/2022 | Bohemians Praha 1905 | - | FK Mladá Boleslav | 2:2 |  |
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| 26. Round | 19/03/2022 | Bohemians Praha 1905 | - | 1. FC Slovácko | 1:2 |  |
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| 27. Round | 03/04/2022 | MFK Karviná | - | Bohemians Praha 1905 | 1:1 |
Czech Republic