4. Round | 05/02/2022 | CF América [U20] | - | Atlético San Luis [U20] | 0:1 | ||||
7. Round | 26/02/2022 | Pumas UNAM [U20] | - | CF América [U20] | 0:1 | ||||
8. Round | 01/03/2022 | CF América [U20] | - | Gallos Blancos [U20] | 2:0 | ||||
10. Round | 12/03/2022 | Deportivo Guadalajara [U20] | - | CF América [U20] | 0:2 | ||||
15. Round | 20/04/2022 | CF América [U20] | - | Club León [U20] | 2:1 |