| Recalificación | 22/04/2022 | Cimarrones de Sonora | - | Tapatío | 2:1 |  |
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| Quarter-finals | 27/04/2022 | Cimarrones de Sonora | - | Alebrijes de Oaxaca | 1:0 dec. | ||||
| Quarter-finals | 30/04/2022 | Alebrijes de Oaxaca | - | Cimarrones de Sonora | 0:0 |  |
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| Semi-finals | 06/05/2022 | Cimarrones de Sonora | - | Club Celaya | 1:0 | |
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| Semi-finals | 08/05/2022 | Club Celaya | - | Cimarrones de Sonora | 1:1 | |
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| Final | 12/05/2022 | Cimarrones de Sonora | - | Atlético Morelia | 0:0 | ||||
| Final | 14/05/2022 | Atlético Morelia | - | Cimarrones de Sonora | 2:0 |
Mexico