| 1. Round | 13/09/2000 | Slavia Praha | - | Akademisk BK | 3:0 | ||||
| 1. Round | 27/09/2000 | Akademisk BK | - | Slavia Praha | 0:2 | ||||
| 2. Round | 25/10/2000 | OFI Heraklion | - | Slavia Praha | 2:2 | ||||
| 2. Round | 08/11/2000 | Slavia Praha | - | OFI Heraklion | 4:1 | ||||
| 3. Round | 22/11/2000 | NK Osijek | - | Slavia Praha | 2:0 | ||||
| 3. Round | 06/12/2000 | Slavia Praha | - | NK Osijek | 5:1 |  |
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| Round of 16 | 14/02/2001 | Slavia Praha | - | 1. FC Kaiserslautern | 0:0 | ||||
| Round of 16 | 21/02/2001 | 1. FC Kaiserslautern | - | Slavia Praha | 1:0 |
Czech Republic