| 1. Round | 06/08/2022 | FC Emmenbrücke | - | FC Solothurn | 2:3 | ||||
| 2. Round | 13/08/2022 | FC Solothurn | - | FC Muri | 6:2 |  |
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| 4. Round | 26/08/2022 | FC Solothurn | - | FC Thun Berner Oberland II | 1:1 | ||||
| 3. Round | 31/08/2022 | FC Wohlen | - | FC Solothurn | 3:2 | ||||
| 5. Round | 03/09/2022 | FC Köniz | - | FC Solothurn | 2:1 |  |
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| 6. Round | 10/09/2022 | FC Solothurn | - | SR Delémont | 3:2 | ||||
| 7. Round | 17/09/2022 | FC Langenthal | - | FC Solothurn | 2:3 | ||||
| 8. Round | 24/09/2022 | FC Solothurn | - | FC Münsingen | 2:1 | ||||
| 9. Round | 01/10/2022 | Neuchâtel Xamax II | - | FC Solothurn | 3:0 | ||||
| 10. Round | 08/10/2022 | FC Schötz | - | FC Solothurn | 2:1 | ||||
| 11. Round | 15/10/2022 | FC Solothurn | - | FC Rotkreuz | 0:0 | |
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| 12. Round | 29/10/2022 | SC Dornach | - | FC Solothurn | 0:2 | ||||
| 13. Round | 05/11/2022 | FC Solothurn | - | FC Bassecourt | 5:1 | ||||
| 14. Round | 13/11/2022 | FC Black Stars Basel | - | FC Solothurn | 4:2 | ||||
| 15. Round | 19/11/2022 | FC Solothurn | - | FC Concordia Basel | 2:1 | ||||
| 16. Round | 26/11/2022 | FC Solothurn | - | FC Emmenbrücke | 1:1 |
Switzerland