| 1° División | 18/04/21 | CF América | - | Cruz Azul | 1:1 | ||||
| 1° División | 28/05/21 | Santos Laguna | - | Cruz Azul | 0:1 | ||||
| 1° División | 15/08/21 | Cruz Azul | - | Deportivo Toluca | 4:0 | ||||
| 1° División | 04/11/21 | Cruz Azul | - | Club León | 0:1 | ||||
| 1° División | 22/11/21 | Cruz Azul | - | CF Monterrey | 1:4 |
| 1° División | 18/04/21 | CF América | - | Cruz Azul | 1:1 | ||||
| 1° División | 28/05/21 | Santos Laguna | - | Cruz Azul | 0:1 | ||||
| 1° División | 15/08/21 | Cruz Azul | - | Deportivo Toluca | 4:0 | ||||
| 1° División | 04/11/21 | Cruz Azul | - | Club León | 0:1 | ||||
| 1° División | 22/11/21 | Cruz Azul | - | CF Monterrey | 1:4 |
| Guillermo Matías Fernández | |
| Born: | 11.10.1991 |
| Place of birth: |
Granadero Baigorria, 
Argentina |
| Nationality: |
Argentina
|
| Height: | 176 cm |
| Weight: | 74 kg |
| Position(s): | Central Midfielder Defensive Midfielder |
| Foot: | right |