| 1. Round | 03/09/2021 | Persikabo 1973 | - | Madura United | 1:1 | ||||
| 2. Round | 12/09/2021 | Madura United | - | PSM Makassar | 1:1 |  |
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| 3. Round | 18/09/2021 | Bhayangkara Presisi Indonesia | - | Madura United | 1:0 | |
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| 4. Round | 25/09/2021 | Madura United | - | PSS Sleman | 1:0 | ||||
| 5. Round | 29/09/2021 | PSIS Semarang | - | Madura United | 0:0 | ||||
| 6. Round | 03/10/2021 | Madura United | - | Persipura Jayapura | 2:2 | |
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| 8. Round | 22/10/2021 | Madura United | - | Persija Jakarta | 2:3 | |
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| 9. Round | 27/10/2021 | Persiraja Banda Aceh | - | Madura United | 1:2 | |
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| 10. Round | 01/11/2021 | Madura United | - | Arema Cronus FC | 1:2 | |
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| 11. Round | 06/11/2021 | Madura United | - | Persita Tangerang | 1:2 | |
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| 12. Round | 20/11/2021 | Persebaya Surabaya | - | Madura United | 1:0 | |
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| 17. Round | 14/12/2021 | Madura United | - | Borneo FC | 2:2 |
Brazil