| 1. Round | 06/06/2022 | Lanús II | - | Rosario Central II | 2:2 | ||||
| 2. Round | 10/06/2022 | Rosario Central II | - | Huracán II | 3:3 | ||||
| 3. Round | 15/06/2022 | Godoy Cruz II | - | Rosario Central II | 1:1 | ||||
| 5. Round | 24/06/2022 | Gimnasia de La Plata II | - | Rosario Central II | 0:1 | ||||
| 6. Round | 02/07/2022 | Rosario Central II | - | Aldosivi II | 5:1 | ||||
| 7. Round | 08/07/2022 | Sarmiento de Junín II | - | Rosario Central II | 1:2 | ||||
| 8. Round | 14/07/2022 | Rosario Central II | - | Independiente II | 5:1 | ||||
| 9. Round | 18/07/2022 | Newell's Old Boys II | - | Rosario Central II | 2:1 | ||||
| 10. Round | 23/07/2022 | Rosario Central II | - | Arsenal de Sarandí II | 2:1 |
Argentina