| 1. Round | 30/09/2004 | CD Nacional | - | Sevilla FC | 1:2 |  |
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| Group H | 04/11/2004 | Sevilla FC | - | Alemannia Aachen | 2:0 | ||||
| Group H | 25/11/2004 | Zenit St. Petersburg | - | Sevilla FC | 1:1 | ||||
| Group H | 02/12/2004 | Sevilla FC | - | AEK Athen | 3:2 | ||||
| 3. Round | 16/02/2005 | Panathinaikos | - | Sevilla FC | 1:0 | ||||
| 3. Round | 24/02/2005 | Sevilla FC | - | Panathinaikos | 2:0 | ||||
| Round of 16 | 17/03/2005 | Parma FC | - | Sevilla FC | 1:0 |
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