| 18. Round | 08/01/2022 | 1899 Hoffenheim | - | FC Augsburg | 3:1 | ||||
| 19. Round | 16/01/2022 | FC Augsburg | - | Eintracht Frankfurt | 1:1 | ||||
| 20. Round | 22/01/2022 | Bayer Leverkusen | - | FC Augsburg | 5:1 | ||||
| 22. Round | 12/02/2022 | Bor. Mönchengladbach | - | FC Augsburg | 3:2 | ||||
| 23. Round | 19/02/2022 | FC Augsburg | - | SC Freiburg | 1:2 | ||||
| 24. Round | 27/02/2022 | FC Augsburg | - | Borussia Dortmund | 1:1 | ||||
| 28. Round | 03/04/2022 | FC Augsburg | - | VfL Wolfsburg | 3:0 | ||||
| 26. Round | 06/04/2022 | FC Augsburg | - | 1. FSV Mainz 05 | 2:1 | ||||
| 29. Round | 09/04/2022 | Bayern München | - | FC Augsburg | 1:0 | ||||
| 30. Round | 16/04/2022 | FC Augsburg | - | Hertha BSC | 0:1 | ||||
| 33. Round | 08/05/2022 | RB Leipzig | - | FC Augsburg | 4:0 |
USA
Mexico 
