| 1. Round | 17/09/1980 | Jeunesse Esch | - | Spartak Moskva | 0:5 | ||||
| 1. Round | 01/10/1980 | Spartak Moskva | - | Jeunesse Esch | 4:0 | ||||
| Round of 16 | 22/10/1980 | Spartak Moskva | - | Esbjerg fB | 3:0 | ||||
| Round of 16 | 05/11/1980 | Esbjerg fB | - | Spartak Moskva | 2:0 | ||||
| Quarter-finals | 04/03/1981 | Spartak Moskva | - | Real Madrid | 0:0 | ||||
| Quarter-finals | 19/03/1981 | Real Madrid | - | Spartak Moskva | 2:0 |  |
Russia
USSR