| 8. Round | 28/08/2021 | Municipal Grecia | - | Sporting FC | 1:1 | ||||
| 9. Round | 07/09/2021 | Guadalupe | - | Municipal Grecia | 0:2 | ||||
| 10. Round | 12/09/2021 | Municipal Grecia | - | CS Herediano | 1:2 | ||||
| 11. Round | 15/09/2021 | Municipal Grecia | - | AD San Carlos | 3:2 | ||||
| 12. Round | 19/09/2021 | CS Cartaginés | - | Municipal Grecia | 1:1 | ||||
| 13. Round | 26/09/2021 | Municipal Grecia | - | Santos de Guápiles | 3:2 | ||||
| 14. Round | 02/10/2021 | Jicaral | - | Municipal Grecia | 3:1 | ||||
| 15. Round | 13/10/2021 | Municipal Grecia | - | AD Guanacasteca | 3:1 |  |
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| 20. Round | 21/11/2021 | Municipal Grecia | - | Guadalupe | 0:0 | |
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| 21. Round | 24/11/2021 | CS Herediano | - | Municipal Grecia | 2:0 | ||||
| 22. Round | 28/11/2021 | AD San Carlos | - | Municipal Grecia | 1:3 |
Costa Rica