| 1. Round | 09/01/2022 | CF Monterrey | - | Gallos Blancos | 0:0 |  |
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| 2. Round | 15/01/2022 | Club Necaxa | - | CF Monterrey | 0:4 |  |
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| 3. Round | 23/01/2022 | CF Monterrey | - | Cruz Azul | 2:2 | |
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| 6. Round | 19/02/2022 | Puebla FC | - | CF Monterrey | 1:0 | ||||
| 7. Round | 26/02/2022 | CF Monterrey | - | Atlético San Luis | 0:2 | ||||
| 8. Round | 02/03/2022 | Club León | - | CF Monterrey | 0:0 | |
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| 9. Round | 06/03/2022 | CF Monterrey | - | CF América | 2:1 | |
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Argentina
USA 