| 12. Round | 01/05/2021 | Sagan Tosu | - | Tokushima Vortis | 2:0 | ||||
| 14. Round | 15/05/2021 | Oita Trinita | - | Sagan Tosu | 1:1 | ||||
| 16. Round | 26/05/2021 | Hokkaido Consadole Sapporo | - | Sagan Tosu | 0:0 | ||||
| 23. Round | 09/08/2021 | Sagan Tosu | - | FC Tokyo | 1:0 | ||||
| 26. Round | 25/08/2021 | Sagan Tosu | - | Yokohama F. Marinos | 0:4 | ||||
| 32. Round | 16/10/2021 | Sagan Tosu | - | Shonan Bellmare | 1:1 | ||||
| 34. Round | 03/11/2021 | Yokohama FC | - | Sagan Tosu | 0:0 | ||||
| 35. Round | 07/11/2021 | Sagan Tosu | - | Kawasaki Frontale | 3:1 |  |
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| 36. Round | 20/11/2021 | Sagan Tosu | - | Hokkaido Consadole Sapporo | 1:0 | ||||
| 37. Round | 27/11/2021 | Kashima Antlers | - | Sagan Tosu | 1:0 | ||||
| 38. Round | 04/12/2021 | Sagan Tosu | - | Vissel Kobe | 0:2 |
Japan