| 1. Round | 21/08/2021 | USV Eschen/Mauren | - | FC Uzwil | 4:0 | ||||
| 2. Round | 28/08/2021 | FC Uzwil | - | FC Thalwil | 1:2 | ||||
| 3. Round | 04/09/2021 | FC Gossau | - | FC Uzwil | 1:1 | ||||
| 5. Round | 18/09/2021 | FC Wettswil-Bonstetten | - | FC Uzwil | 1:2 | ||||
| 6. Round | 25/09/2021 | FC Uzwil | - | FC Paradiso | 1:1 | ||||
| 9. Round | 24/10/2021 | FC Winterthur II | - | FC Uzwil | 1:3 | ||||
| 10. Round | 30/10/2021 | FC Lugano II | - | FC Uzwil | 3:3 | ||||
| 11. Round | 06/11/2021 | FC Uzwil | - | FC Balzers | 3:2 | ||||
| 13. Round | 20/11/2021 | FC Uzwil | - | FC Linth 04 | 4:2 | ||||
| 14. Round | 27/11/2021 | FC Uzwil | - | USV Eschen/Mauren | 2:2 | ||||
| 15. Round | 05/03/2022 | FC Thalwil | - | FC Uzwil | 0:3 | ||||
| 16. Round | 12/03/2022 | FC Uzwil | - | FC Gossau | 2:1 | ||||
| 20. Round | 09/04/2022 | FC Uzwil | - | FC Freienbach | 0:1 | ||||
| 18. Round | 13/04/2022 | FC Uzwil | - | FC Wettswil-Bonstetten | 0:2 | ||||
| 19. Round | 20/04/2022 | FC Paradiso | - | FC Uzwil | 1:0 |  |
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| 21. Round | 23/04/2022 | FC St. Gallen II | - | FC Uzwil | 3:2 | ||||
| 22. Round | 30/04/2022 | FC Uzwil | - | FC Winterthur II | 1:0 | ||||
| 23. Round | 07/05/2022 | FC Uzwil | - | FC Lugano II | 3:2 | ||||
| 24. Round | 14/05/2022 | FC Balzers | - | FC Uzwil | 7:3 | ||||
| 25. Round | 21/05/2022 | FC Uzwil | - | FC Tuggen | 1:2 |
Switzerland
Australia