| 3. Round | 28/08/2021 | Team Aargau [U16] | - | FC Luzern [U16] | 1:5 |  |
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| 4. Round | 05/09/2021 | FC Winterthur [U16] | - | FC Luzern [U16] | 2:5 | |
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| 5. Round | 11/09/2021 | FC Luzern [U16] | - | Team Ticino [U16] | 3:3 | |
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| 7. Round | 25/09/2021 | FC Luzern [U16] | - | Grasshopper Club Zürich [U16] | 1:1 |  |
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| 8. Round | 02/10/2021 | FCO St. Gallen/Wil [U16] | - | FC Luzern [U16] | 3:2 | ||||
| 9. Round | 09/10/2021 | FC Luzern [U16] | - | Team Vaud Lausanne [U16] | 1:4 | |
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| 13. Round | 13/10/2021 | FC Thun Berner Oberland [U16] | - | FC Luzern [U16] | 2:6 | |
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| 10. Round | 16/10/2021 | Team Xamax-BEJUNE FA [U16] | - | FC Luzern [U16] | 2:3 | |
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| 11. Round | 30/10/2021 | FC Luzern [U16] | - | FC Zürich [U16] | 1:0 | ||||
| 12. Round | 06/11/2021 | FC Basel 1893 [U16] | - | FC Luzern [U16] | 3:1 | |
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| 17. Round | 05/03/2022 | FC Luzern [U16] | - | FC Winterthur [U16] | 3:1 | ||||
| 18. Round | 12/03/2022 | Team Ticino [U16] | - | FC Luzern [U16] | 2:3 | ||||
| 19. Round | 19/03/2022 | FC Luzern [U16] | - | BSC Young Boys [U16] | 2:2 |
Switzerland