| 1. Round | 21/08/2021 | Lancy FC | - | FC Echallens | 0:3 | ||||
| 2. Round | 28/08/2021 | FC Meyrin | - | FC Echallens | 6:2 | ||||
| 3. Round | 04/09/2021 | FC Echallens | - | US Terre Sainte | 2:1 | ||||
| 4. Round | 11/09/2021 | Vevey-Sports | - | FC Echallens | 1:0 | ||||
| 5. Round | 18/09/2021 | FC Echallens | - | FC Monthey | 3:3 |  |
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| 6. Round | 25/09/2021 | Team Vaud Lausanne [U21] | - | FC Echallens | 1:3 | ||||
| 7. Round | 02/10/2021 | FC Echallens | - | FC Thun Berner Oberland II | 2:0 |  |
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| 8. Round | 16/10/2021 | FC La Sarraz-Eclépens | - | FC Echallens | 0:0 | ||||
| 9. Round | 23/10/2021 | FC Echallens | - | CS Chênois | 4:0 | ||||
| 10. Round | 30/10/2021 | FC Bulle | - | FC Echallens | 3:4 | |
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| 11. Round | 06/11/2021 | FC Echallens | - | FC Martigny Sports | 2:0 | |
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| 12. Round | 13/11/2021 | FC La Chaux-de-Fonds | - | FC Echallens | 1:3 | |
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| 13. Round | 20/11/2021 | FC Echallens | - | FC Naters | 5:0 | |
France