| 1. Round | 07/07/2021 | KF Teuta Durrës | - | FC Sheriff | 0:4 | ||||
| 1. Round | 13/07/2021 | FC Sheriff | - | KF Teuta Durrës | 1:0 | ||||
| 2. Round | 20/07/2021 | FC Alashkert | - | FC Sheriff | 0:1 | ||||
| 2. Round | 28/07/2021 | FC Sheriff | - | FC Alashkert | 3:1 |  |
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| 3. Round | 03/08/2021 | Crvena Zvezda | - | FC Sheriff | 1:1 | ||||
| 3. Round | 10/08/2021 | FC Sheriff | - | Crvena Zvezda | 1:0 | ||||
| Play-offs | 17/08/2021 | FC Sheriff | - | Dinamo Zagreb | 3:0 | ||||
| Play-offs | 25/08/2021 | Dinamo Zagreb | - | FC Sheriff | 0:0 |
Luxembourg