| 1. Round | 21/08/2021 | FC Martigny Sports | - | FC Monthey | 1:3 | ||||
| 2. Round | 28/08/2021 | Team Vaud Lausanne [U21] | - | FC Martigny Sports | 1:2 | ||||
| 4. Round | 12/09/2021 | FC La Sarraz-Eclépens | - | FC Martigny Sports | 2:1 | ||||
| 6. Round | 25/09/2021 | FC Bulle | - | FC Martigny Sports | 6:0 | ||||
| 5. Round | 29/09/2021 | FC Martigny Sports | - | CS Chênois | 0:1 |  |
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| 7. Round | 02/10/2021 | FC Martigny Sports | - | FC Meyrin | 2:6 | ||||
| 8. Round | 16/10/2021 | FC Martigny Sports | - | FC La Chaux-de-Fonds | 1:3 | ||||
| 10. Round | 30/10/2021 | FC Martigny Sports | - | Lancy FC | 1:2 |  |
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| 12. Round | 13/11/2021 | FC Martigny Sports | - | US Terre Sainte | 2:3 |  |
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| 13. Round | 20/11/2021 | Vevey-Sports | - | FC Martigny Sports | 1:3 | ||||
| 14. Round | 28/11/2021 | FC Monthey | - | FC Martigny Sports | 1:3 |
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