1. Round | 28/08/2021 | SBV Excelsior [U21] | - | Willem II [U21] | 0:1 | ||||
2. Round | 11/09/2021 | Willem II [U21] | - | PEC Zwolle [U21] | 1:1 | ||||
3. Round | 18/09/2021 | FC Emmen [U21] | - | Willem II [U21] | 3:4 | ||||
6. Round | 16/10/2021 | Willem II [U21] | - | De Graafschap [U21] | 1:2 | ||||
9. Round | 06/11/2021 | Alphense Boys [U21] | - | Willem II [U21] | 0:3 |