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| 18/09/2021 | 13:30 | PEC Zwolle | - | Vitesse | 1:0 (0:0) | |
| 14:00 | Roda JC Kerkrade | - | De Graafschap | 3:3 (1:0) | ||
| 14:15 | Alphense Boys | - | SBV Excelsior | 1:0 (1:0) | ||
| 14:30 | FC Emmen | - | Willem II | 3:4 (2:1) |
| » Tables | Home | Away | First round | Second round | First half | Second half |
| # | Team | M. | W | D | L | goals | Dif. | Pt. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Alphense Boys | 3 | 3 | 0 | 0 | 6:2 | 4 | 9 |
| 2 |
|
Willem II | 3 | 2 | 1 | 0 | 6:4 | 2 | 7 |
| 3 |
|
PEC Zwolle | 3 | 2 | 1 | 0 | 4:2 | 2 | 7 |
| 4 |
|
FC Emmen | 3 | 1 | 1 | 1 | 8:7 | 1 | 4 |
| 5 |
|
SBV Excelsior | 3 | 1 | 0 | 2 | 1:2 | -1 | 3 |
| 6 |
|
Roda JC Kerkrade | 3 | 0 | 2 | 1 | 5:7 | -2 | 2 |
| 7 |
|
De Graafschap | 3 | 0 | 1 | 2 | 4:6 | -2 | 1 |
| 8 |
|
Vitesse | 3 | 0 | 0 | 3 | 3:7 | -4 | 0 |
| Promotion | |
| Relegation |
