| 1. Round | 15/07/2000 | Yverdon Sport FC | - | FC Zürich | 1:1 | ||||
| 2. Round | 18/07/2000 | Lausanne Sports | - | Yverdon Sport FC | 4:2 | ||||
| 5. Round | 05/08/2000 | Yverdon Sport FC | - | FC Basel 1893 | 1:0 | ||||
| 6. Round | 12/08/2000 | FC Luzern | - | Yverdon Sport FC | 2:0 | ||||
| 7. Round | 19/08/2000 | Yverdon Sport FC | - | Grasshopper Club Zürich | 2:3 | ||||
| 8. Round | 26/08/2000 | Yverdon Sport FC | - | Servette FC | 2:1 | ||||
| 11. Round | 16/09/2000 | FC Aarau | - | Yverdon Sport FC | 4:3 | ||||
| 12. Round | 22/09/2000 | FC Zürich | - | Yverdon Sport FC | 5:0 | ||||
| 13. Round | 01/10/2000 | Yverdon Sport FC | - | Lausanne Sports | 2:0 | ||||
| 15. Round | 21/10/2000 | Yverdon Sport FC | - | Neuchâtel Xamax FC | 4:0 |  |
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| 14. Round | 24/10/2000 | FC Sion | - | Yverdon Sport FC | 0:0 | ||||
| 16. Round | 29/10/2000 | FC Basel 1893 | - | Yverdon Sport FC | 2:1 | ||||
| 17. Round | 01/11/2000 | Yverdon Sport FC | - | FC Luzern | 3:1 | ||||
| 18. Round | 05/11/2000 | Grasshopper Club Zürich | - | Yverdon Sport FC | 1:0 | ||||
| 20. Round | 25/11/2000 | Yverdon Sport FC | - | FC Lugano | 1:1 | ||||
| 22. Round | 10/12/2000 | Yverdon Sport FC | - | FC Aarau | 3:3 |
Switzerland