| 10. Round | 18/10/2020 | MŠK Žilina | - | Spartak Trnava | 2:1 | ||||
| 11. Round | 24/10/2020 | MFK Ružomberok | - | MŠK Žilina | 2:1 | ||||
| 12. Round | 31/10/2020 | MŠK Žilina | - | FK Senica | 3:1 |  |
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| 13. Round | 08/11/2020 | FC Nitra | - | MŠK Žilina | 0:3 | ||||
| 14. Round | 21/11/2020 | MŠK Žilina | - | AS Trenčín | 2:0 | ||||
| 15. Round | 28/11/2020 | MŠK Žilina | - | FK Pohronie | 2:1 | ||||
| 17. Round | 12/12/2020 | MŠK Žilina | - | ŠKF Sereď | 0:0 | ||||
| 19. Round | 13/02/2021 | MŠK Žilina | - | Zlaté Moravce | 4:1 |  |
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| 20. Round | 21/02/2021 | FC DAC 1904 | - | MŠK Žilina | 1:1 | |
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| 21. Round | 27/02/2021 | Spartak Trnava | - | MŠK Žilina | 2:1 | ||||
| 22. Round | 06/03/2021 | MŠK Žilina | - | MFK Ružomberok | 3:2 |
Nigeria
Portugal