| 16. Round | 26/02/2022 | Grasshopper Club Zürich [U16] | - | FC Thun Berner Oberland [U16] | 2:0 |  |
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| 17. Round | 05/03/2022 | Servette FC [U16] | - | Grasshopper Club Zürich [U16] | 2:0 | ||||
| 18. Round | 12/03/2022 | Grasshopper Club Zürich [U16] | - | FC Sion [U16] | 2:3 | ||||
| 19. Round | 23/03/2022 | Team Aargau [U16] | - | Grasshopper Club Zürich [U16] | 3:1 | ||||
| 21. Round | 09/04/2022 | Team Ticino [U16] | - | Grasshopper Club Zürich [U16] | 1:1 | |
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| 22. Round | 23/04/2022 | Grasshopper Club Zürich [U16] | - | BSC Young Boys [U16] | 2:2 | ||||
| 23. Round | 30/04/2022 | Grasshopper Club Zürich [U16] | - | FC Winterthur [U16] | 4:5 | ||||
| 24. Round | 07/05/2022 | FCO St. Gallen/Wil [U16] | - | Grasshopper Club Zürich [U16] | 1:1 |
Switzerland